Martinez was initially set to bat third and be the designated hitter, but he was removed from the lineup about 2 1/2 hours before first pitch.
Manager Alex Cora said the wrist is sore after Martinez went aggressively into second base during the third inning of a 5-2 win over the Yankees on Friday.
Cora said Martinez may be available to pinch hit. Martinez is considered day to day.
After struggling during the pandemic-shortened 2020 season, the 33-year-old is hitting .321 with 12 homers and a .958 OPS this year.
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