Not only have City rested their best players for the tie to ensure a win, but, after Pep Guardiola’s side lost to Leeds United at the weekend they will be keen to return to their winning ways.
However, Edin Terzic’s men are heading into the match off of a thrilling 3-2 win over VfB Stuttgart in the Bundesliga and so all is to play for.
Here’s everything you need to know about the match.
When is it?
The match will kick off at 8pm GMT on Wednesday, April 14.
How can I watch it?
The fixture will air live on BT Sport 3. Subscribers can also stream the action live on the broadcaster’s website and app.
What is the team news?
While Jadon Sancho has returned to training, he will not feature in the match and despite having injury scares at the weekend both Marcos Reus and Mats Hummels should be fit for the fixture.
Meanwhile for City, after they were rested at the weekend stars Ruben Dias, Rodri, Ilkay Gundogan, Phil Foden, Riyad Mahrez and Kevin De Bruyne are all expected to star.
Dortmund: Hitz; Meunier, Akanji, Hummels, Guerreiro; Can, Bellingham, Dahoud; Knauff, Haaland, Reus
Man City: Ederson; Walker, Dias, Stones, Cancelo; Rodri, Gundogan, De Bruyne; Mahrez, Silva, Foden
Man City: 15/8
City could have more firepower with their rested players raring to go and they will want to get their side back to winning ways after they fell to defeat against Leeds United at the weekend. Despite Dortmund having star quality in Haaland, it won’t be enough to overcome the lead City already have. Dortmund 1-3 Manchester City (agg 2-5).