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Carolina Panthers running back Christian McCaffrey (22)
Fantasy drafters hope a fully healthy Christian McCaffrey will be on display in Week 1. (Photo by Zach Bolinger/Icon Sportswire via Getty Images)

Another fantasy draft season, another year of Christian McCaffrey being the No. 1 overall pick.

We’ve already seen what McCaffrey can do at the height of his powers (a 1,000-1,000 season, anyone?), but last year also showed us that even he can be subject to bad injury luck.

McCaffrey drafters had to suffer a few weeks sans their No. 1 overall pick, while other fantasy managers savvy (or quick) enough to grab Mike Davis off the waiver wire enjoyed a few league-winning weeks.

How will McCaffrey do in Week 1 of 2021, running behind a new quarterback and more weapons on offense?

Check out McCaffrey and the rest of the RBs in our analysts’ positional rankings for Week 1.

2021 Fantasy Football Rankings powered by FantasyProsECR ™ – Expert Consensus Rankings

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